The basic knowledge of benign prostate hyperplasia

The basic knowledge of benign prostate hyperplasia
1.Definition
Benign prostate hyperplasia is common benign disease which can incur elder and middle men having difficulty in urination. Its main symptoms are prostatic stroma and the elements of prostate’s hyperplasia in histology, prostatitis pain enlargement, abnormal lower urinary tract in anatomy, and bladder outlet obstruction in urodynamics.
2.Epidemiology
The incidence of benign prostate hyperplasia will increase as male people grow up in epidemiology. Originally, the disease is usually found after 40 years old. At the age of 60, the person with the disease will account for over 50%, while there will have 83% of persons who will develop the disease at the age of 80. It is similar to histology in symptoms. The symptoms of difficulty in urination will increase as the age grows. In the diagnosis of histology, there are about 50% men who will develop the serious symptoms in lower urinary tract. According to some researches, Asian are easier to develop relevant symptoms about benign prostate hyperplasia than American prostatitis pain.
3.Aetiology
There are indispensable conditions for the developing benign prostate hyperplasia that are the rise of age and orchises which are functional. Our domestic researchers have surveyed some elder person, among whose prostate gland have obvious withered. But specific mechanism of developing benign prostate hyperplasia is not clear. It is possible because the infringement of hyperplasia of epithele and interstitial cells, and the withering of cells causes the case. The relevant factors include the interaction male hormone with female hormone, prostatic stroma- the interation of glandular epithelial cells, growing factors, inflammatory cells, neurotransmitter and heredity.
4.pathology
prostatitis back pain There are some scientists who class prostate gland into peripheral zone, central zone, transitional zone, and prostate gland around urinary tract. All tubercles of benign prostate hyperplasia develop in transitional zone and prostate gland around urinary tract. In original stage, tubercles are all interstitial component around urinary tract；while tubercles in transitional zone will have the reflection of the hyperplasia of prostate tissue; and the number of mesenchyme will decrease. In addition, smooth muscle in interstitial tissue is also very important elements to be made of prostate gland. The smooth muscle and tissue around urinary tract are controlled by adenine nerve in kidney, cholinergic nerve, and other enzymatic neurotransmitter, among which adenine nerve in kidney has a main effect. There is ample α receptor at the tip of prostate and bladder, particularly α 1 receptor. We will obviously reduce the obstruction of urinary tract if the adrenalin can be activated. What is more, the anatomic capsule of prostate has a close relation with the symptoms of urinary tract. Owing to the existence of the anatomic capsule, enlarged body of gland is pressed, bulging into urinary tract and bladder, then causing the aggravation of blocking urinary tract.
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